Article
Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma.
PLoS genetics - 1 Feb 2011
Veth Kerry N, Willer Jason R, Collery Ross F, Gray Matthew P, Willer Gregory B, Wagner Daniel S, Mullins Mary C, Udvadia Ava J, Smith Richard S, John Simon W M, Gregg Ronald G, Link Brian A
Abstract excerpt
The glaucomas comprise a genetically complex group of retinal neuropathies that typically occur late in life and are characterized by progressive pathology of the optic nerve head and degeneration of retinal ganglion cells. In addition to age and family history, other significant risk factors for glaucoma include elevated intraocular pressure (IOP) and myopia. The complexity of glaucoma has made it difficult to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.