Article
Mechanical phenotype is important for stromal aromatase expression.
Steroids - 1 Jul 2011
Ghosh Sagar, Kang Tao, Wang Howard, Hu Yanfen, Li Rong
Abstract excerpt
Evidence that aromatase expression in tumor-associated breast stroma is elevated, provides a rationale for use of aromatase inhibitors (AIs) in breast cancer treatment. However, regulation of local aromatase expression in cancer-free breast stroma is poorly understood. Recent clinical work indicates that stromal cells in dense breast tissue tend to express higher levels of aromatase than their counterpart from...
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