Article
Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women.
Human genetics - 1 Mar 2013
Shi Ting-Yan, Zhu Mei-Ling, He Jing, Wang Meng-Yun, Li Qiao-Xin, Zhou Xiao-Yan, Sun Meng-Hong, Shao Zhi-Ming, Yu Ke-Da, Cheng Xi, Wu Xiaohua, Wei Qingyi
Abstract excerpt
Interleukin 6 (IL6) encodes a cytokine protein, which functions in inflammation, maintains immune homeostasis and plays important roles in cervical carcinogenesis. Single nucleotide polymorphisms (SNPs) in IL6 that cause variations in host immune response may contribute to cervical cancer risk. In this two-stage case-control study with a total of 1,584 cervical cancer cases and 1,768 cancer-free female controls,...
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