Article
Increased warfarin consumption and residual fibrin turnover in thrombotic patients with primary antiphospholipid syndrome.
Thrombosis research - 1 Jun 2011
Ames Paul R J, Margaglione Maurizio, Ciampa Antonio, Colaizzo Donatella, Ferrara Felicetto, Iannaccone Luigi, Vincenzobrancaccio
Abstract excerpt
INTRODUCTION: Anedoctal reports suggest that some thrombotic primary antiphospholipid antibody syndrome (PAPS) patients on oral anticoagulation require higher than average doses to achieve given targets international normalized ratios (INR). MATERIALS AND METHODS: To test the hypothesis of relative warfarin resistance in thrombotic PAPS and the effect of baseline IgG anticardiolipin antibodies, the cytochrome...
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