Article
A monoclonal antibody to human protein S used as the capture antibody for measuring total protein S by enzyme immunoassay.
Clinical chemistry - 1 Jan 1990
Krachmalnicoff A, Tombesi S, Valsecchi C, Albertini A, Mannucci P M
Abstract excerpt
Measurement of Protein S in human plasma is clinically important because of deficiency of this protein, which functions as a cofactor of the naturally occurring anticoagulant activated Protein C, is a risk factor for venous thromboembolism. We describe a two-site, enzyme-linked immunosorbent assay (ELISA) for measuring Protein S in which a monoclonal IgG directed against the calcium-independent conformation of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.