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Article

Clinical management of hereditary breast cancer syndromes.

Journal of mammary gland biology and neoplasia - 1 Apr 2011

Clark Amy S, Domchek Susan M

Abstract excerpt

Over the past 15 years there has been substantial improvement in the understanding of hereditary breast cancer. Germline genetic testing for mutations in BRCA1, BRCA2, PTEN and TP53 allows for the identification of individuals at increased risk for breast, ovarian and other cancers. Advances in screening, prevention and treatment have led to improved clinical management which is best defined for BRCA1 and BRCA2...

Topics

Breast Neoplasms
Breast Self-Examination
Early Detection of Cancer
Early Diagnosis
Female
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease
Humans
Magnetic Resonance Imaging
Mammography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplastic Syndromes, Hereditary

Source

Identifiers

PMID: 21360002
DOI: 10.1007/s10911-011-9200-x

Genes

BRCA1
BRCA2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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