Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study.

doi:10.1016/S1473-3099(11)70032-9

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Article

Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study.

The Lancet. Infectious diseases - 1 May 2011

Wittkop Linda, Günthard Huldrych F, de Wolf Frank, Dunn David, Cozzi-Lepri Alessandro, de Luca Andrea, Kücherer Claudia, Obel Niels, von Wyl Viktor, Masquelier Bernard, Stephan Christoph, Torti Carlo, Antinori Andrea, García Federico, Judd Ali, Porter Kholoud, Thiébaut Rodolphe, Castro Hannah, van Sighem Ard I, Colin Céline, Kjaer Jesper, Lundgren Jens D, Paredes Roger, Pozniak Anton, Clotet Bonaventura, Phillips Andrew, Pillay Deenan, Chêne Geneviève

Abstract excerpt

BACKGROUND: The effect of transmitted drug resistance (TDR) on first-line combination antiretroviral therapy (cART) for HIV-1 needs further study to inform choice of optimum drug regimens. We investigated the effect of TDR on outcome in the first year of cART within a large European collaboration. METHODS: HIV-infected patients of any age were included if they started cART (at least three antiretroviral drugs)...

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Identifiers

PMID: 21354861
DOI: 10.1016/S1473-3099(11)70032-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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