Article
Prevalence of transmitted HIV-1 drug resistance and the role of resistance algorithms: data from seroconverters in the CASCADE collaboration from 1987 to 2003.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2005
Masquelier Bernard, Bhaskaran Krishnan, Pillay Deenan, Gifford Robert, Balestre Eric, Jørgensen Louise Bruun, Pedersen Court, van der Hoek Lia, Prins Maria, Balotta Claudia, Longo Benedetta, Kücherer Claudia, Poggensee Gabriele, Ortiz Marta, de Mendoza Carmen, Gill John, Fleury Hervé, Porter Kholoud
Abstract excerpt
OBJECTIVES: To examine factors influencing the rate of transmitted drug resistance (TDR) among seroconverters, with particular emphasis on 3 widely used genotypic drug resistance algorithms. METHODS: The study used data from CASCADE (Concerted Action on Seroconversion to AIDS and Death in Europe), a collaboration of seroconverter cohorts in Europe and Canada. Genotypic resistance data were derived within 18...
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