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Article

Regulation of lung endoderm progenitor cell behavior by miR302/367

25 Feb 2011

Abstract excerpt

The temporal and spatial control of organ-specific endoderm progenitor development is poorly understood. miRNAs affect cell function by regulating programmatic changes in protein expression levels. We show that the miR302/367 cluster is a target of the transcription factor Gata6 in mouse lung endoderm and regulates multiple aspects of early lung endoderm progenitor development. miR302/367 is expressed at early...

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PMID: 21350014
DOI: 10.1242/dev.061762

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