Article
Behaviour of Telomere and Telomerase during Aging and Regeneration in Zebrafish
9 Feb 2011
Abstract excerpt
Telomere length and telomerase activity are important factors in the pathobiology of human diseases. Age-related diseases and premature aging syndromes are characterized by short telomeres, which can compromise cell viability, whereas tumour cells can prevent telomere loss by aberrantly upregulating telomerase. The zebrafish (Danio rerio) offers multiple experimental manipulation advantages over other vertebrate...
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