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The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases

10 Jan 2019

Abstract excerpt

Cancer is a disease of the elderly, and old age is its largest risk factor. With age, DNA damage accumulates continuously, increasing the chance of malignant transformation. The zebrafish has emerged as an important vertebrate model to study these processes. Key mechanisms such as DNA damage responses and cellular senescence can be studied in zebrafish throughout its life course. In addition, the zebrafish is...

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Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence
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PMID: 30687705
DOI: 10.3389/fcell.2018.00178

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