Quantitative proteomics reveals the dynamics of protein changes during <i>Drosophila</i> oocyte maturation and the oocyte-to-embryo transition

Abstract excerpt

The onset of development is marked by two major, posttranscriptionally controlled, events: oocyte maturation (release of the prophase I primary arrest) and egg activation (release from the secondary meiotic arrest). Using quantitative mass spectrometry, we previously described proteome remodeling during Drosophila egg activation. Here, we describe our quantitative mass spectrometry-based analysis of the changes...

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