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Maternal age effect on mouse oocytes: new biological insight from proteomic analysis

1 Apr 2014

Abstract excerpt

The long-standing view of 'immortal germline vs mortal soma' poses a fundamental question in biology concerning how oocytes age in molecular terms. A mainstream hypothesis is that maternal ageing of oocytes has its roots in gene transcription. Investigating the proteins resulting from mRNA translation would reveal how far the levels of functionally available proteins correlate with mRNAs and would offer novel...

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PMID: 24686459
DOI: 10.1530/rep-14-0126

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