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Isolation of Mesenchymal Stem Cells From Human Ligamentum Flavum

23 Feb 2011

Abstract excerpt

In Brief Study Design. To demonstrate the existence of mesenchymal stem cells (MSCs) in ligamentum flavum (LF) and their pathogenic role in LF hypertrophy. Objective. To isolate and characterize LF-derived MSCs and their response to transforming growth factor-beta 1 (TGF-β1) and trichostatin A (TSA), a histone deacetylase inhibitor (HDACi). Summary of Background Data. LF is a connective tissue, of which...

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PMID: 21343850
DOI: 10.1097/brs.0b013e3182053f58

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