Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.

doi:10.1007/s10038-008-0262-6

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Article

Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.

Journal of human genetics - 1 Jan 2008

Mao Renfang, Fan Yihui, Jin Yan, Bai Jing, Fu Songbin

Abstract excerpt

So far, case-control studies on the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and lung cancer provide controversial or inconclusive results. To clarify the effect of MTHFR polymorphisms on the risk of lung cancer, a meta-analysis of all case-control observational studies was performed. The studies provided 5,111/6,415 cases/controls for C677T and 5,087/6,232 cases/controls...

Topics

Cluster Analysis
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Methylenetetrahydrofolate Reductase (NADPH2)
Models, Genetic
Mutation
Odds Ratio
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 18340404
DOI: 10.1007/s10038-008-0262-6

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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