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Article

Polo-like kinase 2 (SNK/PLK2) is a novel epigenetically regulated gene in acute myeloid leukemia and myelodysplastic syndromes: genetic and epigenetic interactions.

Annals of hematology - 1 Sept 2011

Benetatos Leonidas, Dasoula Aggeliki, Hatzimichael Eleftheria, Syed Nelofer, Voukelatou Maria, Dranitsaris George, Bourantas Konstantinos L, Crook Tim

Abstract excerpt

Polo-like kinase 2 (SNK/PLK2), a transcriptional target for wild-type p53 and is hypermethylated in a high percentage of multiple myeloma and B cell lymphomas patients. Given these data, we sought to study the methylation status of the specific gene in acute myeloid leukemia (AML) and myelodyspla...

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Source

Identifiers

PMID: 21340720
DOI: 10.1007/s00277-011-1193-4

Genes

PLK2
MTHFR
FLT3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21340720-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Polo-like kinase 2 (SNK/PLK2) is a novel epigenetically regulated gene in acute myeloid leukemia and myelodysplastic syndromes: genetic and epigenetic interactions.PMID 21340720Read ↗

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