Article
Artificial neural network weights of residues for the serological specificities of HLA.
International journal of immunogenetics - 1 Jun 2011
Choi S-E, Park C-W, Sohn Y-H, Ko S-Y, Oh H-B, Kim G-H, Kim H
Abstract excerpt
New human leucocyte antigen (HLA) alleles are assigned largely based on their sequence homologies due to lack of information on the serological reactivities. Artificial neural networks (ANNs) have been tested as a possible tool for helping to predict the serology of new alleles in the absence of serological information. However, an ANN analysis per se imparts no information regarding which residues are important...
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