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Article

Graphical classification of DNA sequences of HLA alleles by deep learning.

Human cell - 1 Apr 2018

Miyake Jun, Kaneshita Yuhei, Asatani Satoshi, Tagawa Seiichi, Niioka Hirohiko, Hirano Takashi

Abstract excerpt

Alleles of human leukocyte antigen (HLA)-A DNAs are classified and expressed graphically by using artificial intelligence "Deep Learning (Stacked autoencoder)". Nucleotide sequence data corresponding to the length of 822 bp, collected from the Immuno Polymorphism Database, were compressed to 2-dimensional representation and were plotted. Profiles of the two-dimensional plots indicate that the alleles can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29327117
DOI: 10.1007/s13577-017-0194-6
PMCID: PMC5852191

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