Article
New nucleoside analogs for patients with hematological malignancies
14 Feb 2011
Abstract excerpt
INTRODUCTION: In the last few years, several new purine and pyrimidine nucleoside analogs have been synthesized and made available for both preclinical studies and clinical trials. AREAS COVERED: This article summarizes recent achievements in the mechanism of action, pharmacological properties and clinical activity and toxicity as well as the emerging role of newer purine and pyrimidine nucleoside analogs...
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