Article
Angiotensin II receptor type 1 1166 A/C and angiotensin converting enzyme I/D gene polymorphisms in a Dutch sarcoidosis cohort.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Jul 2010
Kruit A, Ruven H J T, Grutters J C, van den Bosch J M
Abstract excerpt
BACKGROUND: The angiotensin II type 1 receptor (AT2R1) is the receptor for angiotensin II, a potent vasoconstrictor produced by ACE from angiotensin I. A recent study by Biller and colleagues revealed a gender-specific association between the AT2R1 1166 A/C gene polymorphism and disease susceptibility as well as a co-dependent association between AT2R1 1166 A/C and the angiotensin-converting enzyme (ACE)...
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