Article
Gait disturbances in dystrophic hamsters.
Journal of biomedicine & biotechnology - 1 Jan 2011
Hampton Thomas G, Kale Ajit, Amende Ivo, Tang Wenlong, McCue Scott, Bhagavan Hemmi N, VanDongen Case G
Abstract excerpt
The delta-sarcoglycan-deficient hamster is an excellent model to study muscular dystrophy. Gait disturbances, important clinically, have not been described in this animal model. We applied ventral plane videography (DigiGait) to analyze gait in BIO TO-2 dystrophic and BIO F1B control hamsters walking on a transparent treadmill belt. Stride length was ∼13% shorter (P < .05) in TO-2 hamsters at 9 months of age...
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