Article
Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2011
Cote Michele L, Haddad Ramsi, Edwards David J, Atikukke Govindaraja, Gadgeel Shirish, Soubani Ayman O, Lonardo Fulvio, Bepler Gerold, Schwartz Ann G, Ethier Stephen P
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) predict response to tyrosine kinase inhibitors. Mutations occur more commonly in never smokers and East Asians, but there are conflicting reports on the frequency of EGFR mutations in tumors from African Americans. METHODS: Tumors from 67 African American and 77 white participants in previous case-control studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
