Article
Streptococcus mutans diacylglycerol kinase homologue: a potential target for anti-caries chemotherapy.
Journal of medical microbiology - 1 May 2011
Shibata Yukie, Kawada-Matsuo Miki, Shirai Yasuhito, Saito Naoaki, Li Dan, Yamashita Yoshihisa
Abstract excerpt
Aciduricity is a major cariogenic characteristic of Streptococcus mutans, and various genes have been implicated in this ability of S. mutans. Sixteen S. mutans mutant strains, each defective in a different gene, were constructed and their aciduricity was assessed. Of the mutants, the diacylglycerol kinase (Dgk) homologue mutant and the glucose-1-phosphate uridylyltransferase mutant strains displayed distinctly...
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