Article
uvrA is an acid-inducible gene involved in the adaptive response to low pH in Streptococcus mutans.
Journal of bacteriology - 1 Oct 2001
Hanna M N, Ferguson R J, Li Y H, Cvitkovitch D G
Abstract excerpt
The pH-inducible acid tolerance response (ATR) is believed to play a major role in acid adaptation and virulence of Streptococcus mutans. To study this phenomenon in S. mutans JH1005, differential display PCR was used to identify and clone 13 cDNA products that had increased expression in response to pH 5.0 compared to that of pH 7.5-grown cells. One of these products, confirmed to be pH inducible by RNA dot blot...
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