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Article

Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas.

Brain pathology (Zurich, Switzerland) - 1 Sept 2011

Horbinski Craig, Kofler Julia, Yeaney Gabrielle, Camelo-Piragua Sandra, Venneti Sriram, Louis David N, Perry Arie, Murdoch Geoffrey, Nikiforova Marina

Abstract excerpt

Recent work has identified novel point mutations in isocitrate dehydrogenase 1 (IDH1) in the majority of the World Health Organization grades II and III infiltrative gliomas and secondary grade IV glioblastomas. Gangliogliomas consist of neoplastic ganglion and glial cells and, in contrast to infiltrative gliomas, are generally indolent. Yet distinguishing between a ganglioglioma and an infiltrative glioma with...

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Source

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Identifiers

PMID: 21314850
DOI: 10.1111/j.1750-3639.2011.00480.x
PMCID: PMC3681126

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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