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Regulation of the water channel aquaporin-2 by posttranslational modification

10 Feb 2011

Abstract excerpt

The cellular functions of many eukaryotic membrane proteins, including the vasopressin-regulated water channel aquaporin-2 (AQP2), are regulated by posttranslational modifications. In this article, we discuss the experimental discoveries that have advanced our understanding of how posttranslational modifications affect AQP2 function, especially as they relate to the role of AQP2 in the kidney. We review the most...

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PMID: 21307124
DOI: 10.1152/ajprenal.00721.2010

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