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Article

Loss at chromosome arm 16q in retinoblastoma: confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted region.

Genes, chromosomes & cancer - 1 May 2011

Gustmann Sebastian, Klein-Hitpass Ludger, Stephan Harald, Weber Susanne, Bornfeld Norbert, Kaulisch Marc, Lohmann Dietmar R, Dünker Nicole

Abstract excerpt

In addition to mutations in both alleles of the retinoblastoma gene (RB1) alleles, retinoblastomas frequently show additional alterations including loss of chromosome arm 16q. In a previous study, the presence of 16q alterations was found to be associated with diffuse vitreous seeding of this tumor. This growth pattern is clinically important as it determines therapeutic decisions. The present study was designed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21305643
DOI: 10.1002/gcc.20857

Genes

CDH13

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