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Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

1 Jan 2011

Abstract excerpt

Telomeres are present at the ends of all eukaryotic chromosomes. Human telomeres play an important role in critical processes underlying genome stability, cancer, and aging, and their importance was recognized via the award of the 2009 Nobel Prize in Physiology or Medicine. Chemistry has made vast and almost unparalleled contributions to telomere biology. This critical review highlights the contributions of...

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PMID: 21301727
DOI: 10.1039/c0cs00134a

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