Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

Diabetologia - 1 May 2011

Forbes J M, Söderlund J, Yap F Y T, Knip M, Andrikopoulos S, Ilonen J, Simell O, Veijola R, Sourris K C, Coughlan M T, Forsblom C, Slattery R, Grey S T, Wessman M, Yamamoto H, Bierhaus A, Cooper M E, Groop P-H

Abstract excerpt

AIMS/HYPOTHESIS: This group of studies examines human genetic susceptibility conferred by the receptor for advanced glycation end-products (RAGE) in type 1 diabetes and investigates how this may interact with a western environment. METHODS: We analysed the AGER gene, using 13 tag SNPs, in 3,624 Finnish individuals from the FinnDiane study, followed by AGER associations with a high risk HLA genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mice, Inbred NOD

Share to Polymorphism, Genetic

Share to Receptor for Advanced Glycation End Products

Share to Receptors, Immunologic

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 21298413
DOI: 10.1007/s00125-011-2058-z

Genes

AGER

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.PMID 21298413Read ↗

Advanced glycation end products as environmental risk factors for the development of type 1 diabetes.Semantic proximity Read ↗

Circulating concentrations of soluble receptor for AGE are associated with age and AGER gene polymorphisms in children with newly diagnosed type 1 diabetes.Semantic proximity Read ↗

Pathological Implications of Receptor for Advanced Glycation End-Product (AGER) Gene PolymorphismSemantic proximity Read ↗

Genetic variability in the RAGE gene: possible implications for nutrigenetics, nutrigenomics, and understanding the susceptibility to diabetic complications.Semantic proximity Read ↗

The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients.Semantic proximity Read ↗

Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status.Semantic proximity Read ↗

Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes.Semantic proximity Read ↗

Susceptibility of six polymorphisms in the receptor for advanced glycation end products to type 2 diabetes: a systematic review and meta-analysis.Semantic proximity Read ↗

The effects of Advanced Glycation End Products (RAGE)-374T/A and Gly82Ser variants and soluble-RAGE levels to obesity in children.Semantic proximity Read ↗

Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic diseaseSemantic proximity Read ↗

Genetic variants in the receptor for advanced glycation end products (RAGE) gene were associated with circulating soluble RAGE level but not with renal function among Asians with type 2 diabetes: a genome-wide association study.Semantic proximity Read ↗

Receptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.