Article
Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status.
Metabolism: clinical and experimental - 1 Oct 2001
Kanková K, Márová I, Záhejský J, Muzík J, Stejskalová A, Znojil V, Vácha J
Abstract excerpt
The formation of advanced glycation end products (AGEs) and oxidative stress are supposed to play an important role in the development of diabetic late complications. AGEs can bind to several binding sites including receptor of advanced glycation end products (RAGE). AGE-RAGE interaction results in free radical generation. The aim of the present study was to investigate the impact of previously described...
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