Article
Genome-wide linkage analysis of pulse pressure in Mexican Americans.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2001
Atwood L D, Samollow P B, Hixson J E, Stern M P, MacCluer J W
Abstract excerpt
Pulse pressure, a measure of aortic stiffness, is a strong predictor of cardiovascular mortality. To locate genes that affect pulse pressure, we performed genetic analysis on randomly ascertained families in the San Antonio Family Heart Study. Pulse pressure was defined as the difference between systolic and diastolic blood pressures. Likelihood methods were used to construct a model that had both single-locus...
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