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Article

Lingo2 variants associated with essential tremor and Parkinson's disease.

Human genetics - 1 Jun 2011

Wu Yi-Wen, Prakash K M, Rong Tian-Yi, Li Hui-Hua, Xiao Qin, Tan Louis C, Au Wing-Lok, Ding Jian-qing, Chen Sheng-di, Tan Eng-King

Abstract excerpt

LINGO2, a member of LRR gene family, has been linked with both Essential tremor (ET) and Parkinson's disease (PD). However, there is a lack of conclusive evidence regarding the etiologic role of LINGO2 genetic variants. We investigated the association of LINGO2 variants with ET and PD in two independent Asian countries. A total of 1,262 subjects comprising 499 controls, 436 PD patients, and 327 ET patients were...

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PMID: 21287203
DOI: 10.1007/s00439-011-0955-3

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