Article
LINGO1 rs9652490 is associated with essential tremor and Parkinson disease.
Parkinsonism & related disorders - 1 Feb 2010
Vilariño-Güell Carles, Ross Owen A, Wider Christian, Jasinska-Myga Barbara, Cobb Stephanie A, Soto-Ortolaza Alexandra I, Kachergus Jennifer M, Keeling Brett H, Dachsel Justus C, Melrose Heather L, Behrouz Bahareh, Wszolek Zbigniew K, Uitti Ryan J, Aasly Jan O, Rajput Alex, Farrer Matthew J
Abstract excerpt
Recently, a variant in LINGO1 (rs9652490) was found to associate with increased risk of essential tremor. We set out to replicate this association in an independent case-control series of essential tremor from North America. In addition, given the clinical and pathological overlap between essential tremor and Parkinson disease, we also evaluate the effect of LINGO1 rs9652490 in two case-control series of...
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