Article
LINGO1 polymorphisms are associated with essential tremor in Europeans.
Movement disorders : official journal of the Movement Disorder Society - 30 Apr 2010
Thier Sandra, Lorenz Delia, Nothnagel Michael, Stevanin Giovanni, Dürr Alexandra, Nebel Almut, Schreiber Stefan, Kuhlenbäumer Gregor, Deuschl Günther, Klebe Stephan
Abstract excerpt
Essential tremor (ET) is one of the most common movement disorders. Former association studies focussing on candidate genes in ET found a number of risk variants but most of them were not replicated. Recently, a genome-wide association study revealed two intronic sequence variants in the LINGO1 gene associated with ET. Here, we have confirmed association between sequence variants in the LINGO1 gene and the ET...
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