Article
Investigation on Mycobacterium tuberculosis diversity in China and the origin of the Beijing clade.
PloS one - 1 Jan 2011
Wan Kanglin, Liu Jinghua, Hauck Yolande, Zhang Yuanyuan, Liu Jie, Zhao Xiuqin, Liu Zhiguang, Lu Bing, Dong Haiyan, Jiang Yi, Kremer Kristin, Vergnaud Gilles, van Soolingen Dick, Pourcel Christine
Abstract excerpt
BACKGROUND: Investigation of the genetic diversity of Mycobacterium tuberculosis in China has shown that Beijing genotype strains play a dominant role in the tuberculosis (TB) epidemic. In order to examine the strain diversity in the whole country, and to study the evolutionary development of Beijing strains, we sought to genotype a large collection of isolates using different methods. METHODOLOGY/PRINCIPAL...
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