Article
Evaluation of human leukocyte antigen-A (HLA-A), other non-HLA markers on chromosome 6p21 and risk of nasopharyngeal carcinoma.
PloS one - 1 Jan 2012
Hsu Wan-Lun, Tse Ka-Po, Liang Sharon, Chien Yin-Chu, Su Wen-Hui, Yu Kelly J, Cheng Yu-Juen, Tsang Ngan-Ming, Hsu Mow-Ming, Chang Kai-Ping, Chen I-How, Chen Tzu-I, Yang Czau-Siung, Goldstein Alisa M, Chen Chien-Jen, Chang Yu-Sun, Hildesheim Allan
Abstract excerpt
BACKGROUND: The association between human leukocyte antigen (HLA) genes (located in the Major Histocompatibility Complex [MHC] region of chromosome 6p21) and NPC has been known for some time. Recently, two genome-wide association studies (GWAS) conducted in Taiwan and China confirmed that the strongest evidence for NPC association was mapped to the MHC region. It is still unclear, however, whether these findings...
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