Article
Role of Klebsiella pneumoniae LamB Porin in antimicrobial resistance.
Antimicrobial agents and chemotherapy - 1 Apr 2011
García-Sureda Laura, Juan Carlos, Doménech-Sánchez Antonio, Albertí Sebastián
Abstract excerpt
To investigate the contribution of LamB in Klebsiella pneumoniae antimicrobial resistance, we determined the MICs of various antibiotics and the frequency of mutation to increased cefoxitin or meropenem resistance of the strains CSUB10S (expressing only OmpK36), CSUB10R (lacking OmpK35 and OmpK36), and their derived isogenic insertion-duplication mutants deficient in LamB. Expression of LamB was indispensable in...
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