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Article

Actigraphy Detects Greater Intra-Individual Variability During Gait in Non-Manifesting LRRK2 Mutation Carriers.

Journal of Parkinson's disease - 1 Jan 2018

van den Heuvel Lieneke, Lim Andrew S, Visanji Naomi P, Huang Jana, Ghate Taneera, Mestre Tiago A, AlDakheel Amaal, Connolly Barbara S, Gasca-Salas Carmen, Kern Drew S, Jain Jennifer, Slow Elizabeth J, Pondal Margarita, Faust-Socher Achinoam, Rogaeva Ekaterina, Tomlinson George, Lang Anthony E, Marras Connie

Abstract excerpt

BACKGROUND: With recent advances in the search for disease-modifying therapies for Parkinson's disease (PD) the importance of identifying prodromal markers becomes greater. Non-manifesting LRRK2 mutation carriers (NMC) are at risk for developing PD, and provide a population in which to identify possible markers. OBJECTIVE: The aim of this study was to test the hypothesis that NMC have differences in daily...

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PMID: 29480219
DOI: 10.3233/JPD-171151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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