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Article

The CD18 AvaII polymorphic site not associated with Henoch-Schönlein purpura.

Clinical and experimental rheumatology - 1 Jan 2000

He Xuelian, Li Ying, Kang Shixiu, Luan Jiangwei, Wu Yanxiang, Liu Zhisheng, Yin Wei

Abstract excerpt

Henoch-Schönlein purpura (HSP) is an immune complex-mediated systemic vasculitis. Its genetic etiology remains unknown. CD18, the subunit of integrin beta2 in leukocytes, has essential roles in the expression and function of ITGB2, mediating immune responses. CD18 has been proved to be associated with some systemic vasculitides, such as microscopic polyangiitis and Churg-Strauss syndrome. We aimed to assess the...

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PMID: 21269583

Genes

CRP
ITGB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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