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Article

Sessile serrated adenoma with early neoplastic progression: a clinicopathologic and molecular study.

The American journal of surgical pathology - 1 Feb 2011

Fujita Kohei, Yamamoto Hidetaka, Matsumoto Takayuki, Hirahashi Minako, Gushima Masaki, Kishimoto Junji, Nishiyama Ken-ichi, Taguchi Tomoaki, Yao Takashi, Oda Yoshinao

Abstract excerpt

Sessile serrated adenoma (SSA), also referred to as sessile serrated polyp, has been proposed as a precursor lesion to microsatellite unstable carcinoma. However, the mechanism of stepwise progression from SSA to early invasive carcinoma has been unclear. The purpose of this study was to elucidate the histologic characteristics and possible role of p53, β-catenin, BRAF, KRAS, and PIK3CA in the development and...

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Share to Adenocarcinoma, Mucinous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 21263251
DOI: 10.1097/PAS.0b013e318205df36

Genes

HGD
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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