Article
The impact of self-identified race on epidemiologic studies of gene expression.
Genetic epidemiology - 1 Feb 2011
Sharma Sunita, Murphy Amy, Howrylak Judie, Himes Blanca, Cho Michael H, Chu Jen-Hwa, Hunninghake Gary M, Fuhlbrigge Anne, Klanderman Barbara, Ziniti John, Senter-Sylvia Jody, Liu Andy, Szefler Stanley J, Strunk Robert, Castro Mario, Hansel Nadia N, Diette Gregory B, Vonakis Becky M, Adkinson N Franklin, Carey Vincent J, Raby Benjamin A
Abstract excerpt
Although population differences in gene expression have been established, the impact on differential gene expression studies in large populations is not well understood. We describe the effect of self-reported race on a gene expression study of lung function in asthma. We generated gene expression profiles for 254 young adults (205 non-Hispanic whites and 49 African Americans) with asthma on whom concurrent total...
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