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Article

Psychosocial experiences modulate asthma-associated genes through gene-environment interactions.

eLife - 18 Jun 2021

Resztak Justyna A, Farrell Allison K, Mair-Meijers Henriette, Alazizi Adnan, Wen Xiaoquan, Wildman Derek E, Zilioli Samuele, Slatcher Richard B, Pique-Regi Roger, Luca Francesca

Abstract excerpt

Social interactions and the overall psychosocial environment have a demonstrated impact on health, particularly for people living in disadvantaged urban areas. Here, we investigated the effect of psychosocial experiences on gene expression in peripheral blood immune cells of children with asthma in Metro Detroit. Using RNA-sequencing and a new machine learning approach, we identified transcriptional signatures of...

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Identifiers

PMID: 34142656
DOI: 10.7554/eLife.63852
PMCID: PMC8282343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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