Article
Genome-wide association: from confounded to confident.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry - 1 Apr 2011
Glessner Joseph T, Hakonarson Hakon
Abstract excerpt
Genome-wide association studies (GWAS) allow for a large number of samples to be assayed simultaneously, using a genome-wide tagging single nucleotide polymorphism (SNP) approach. The initial boon of success from disease studies such as macular degeneration and inflammatory bowel disease has been mitigated by lack of genome-wide significance for psychiatric disorders and related traits, despite evaluations of...
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