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Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis B to interferon alfa

20 Jan 2011

Abstract excerpt

In order to examine whether variation in interleukin-10 promoter polymorphism would predict the likelihood of sustain response of chronic hepatitis B to treatment with interferon alfa (IFN-α), the inheritance of 3 biallelic polymorphisms in the IL-10 gene promoter in patients with 52 chronic hepatitis B were determined by polymerase chain reaction (PCR)-bared techniques, restriction enzyme digestion or direct...

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PMID: 21251301
DOI: 10.1186/1743-422x-8-28

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