Article
Preliminary evidence for involvement of the tumour suppressor gene CHD5 in a family with cutaneous melanoma.
The British journal of dermatology - 1 May 2011
Lang J, Tobias E S, Mackie R
Abstract excerpt
BACKGROUND: Cutaneous melanoma is rapidly increasing in incidence worldwide and approximately 5% of melanomas are hereditary. Deletions in chromosome 1p36 have been detected in melanoma but no candidate melanoma tumour suppressor gene has yet been found in this area. Recently, strong evidence has been reported that CHD5 is a tumour suppressor gene in this region. OBJECTIVES: To investigate CHD5 involvement in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
