Article
Transcriptional regulation of the Zrg17 zinc transporter of the yeast secretory pathway.
The Biochemical journal - 1 Apr 2011
Wu Yi-Hsuan, Frey Avery G, Eide David J
Abstract excerpt
The Msc2 and Zrg17 proteins of Saccharomyces cerevisiae are members of the cation diffusion facilitator family of zinc transporters. These proteins form heteromeric complexes that transport zinc into the ER (endoplasmic reticulum). Previous studies suggested that the ZRG17 gene is regulated in response to zinc status by the Zap1 transcription factor. Zap1 activates the expression of many genes in zinc-deficient...
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