Article
Interactions of Polycomb and trithorax with cis regulatory regions of Ultrabithorax during the development of Drosophila melanogaster.
The EMBO journal - 1 Dec 1990
Castelli-Gair J E, García-Bellido A
Abstract excerpt
The activity of the Ultrabithorax gene is continuously required during imaginal development to maintain the morphogenetic identity of the third thoracic segment of Drosophila. The spatial pattern of Ultrabithorax gene expression depends on certain cis regulatory regions and several trans regulatory genes. Amongst the latter the Polycomb gene is necessary to maintain Ultrabithorax repressed in cells where it was...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Drosophila melanogaster
- Gene Expression Regulation
- Heterozygote
- Mutation
- Regulatory Sequences, Nucleic Acid
- Thorax
- Transformation, Genetic