Article
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jan 2011
Zhang Chi, Montgomery Taiowa A, Gabel Harrison W, Fischer Sylvia E J, Phillips Carolyn M, Fahlgren Noah, Sullivan Christopher M, Carrington James C, Ruvkun Gary
Abstract excerpt
Argonaute-associated siRNAs and Piwi-associated piRNAs have overlapping roles in silencing mobile genetic elements in animals. In Caenorhabditis elegans, mutator (mut) class genes mediate siRNA-guided repression of transposons as well as exogenous RNAi, but their roles in endogenous RNA silencing...
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