Article
Clinical phenotypes in autopsy-confirmed Pick disease.
Neurology - 18 Jan 2011
Piguet O, Halliday G M, Reid W G J, Casey B, Carman R, Huang Y, Xuereb J H, Hodges J R, Kril J J
Abstract excerpt
BACKGROUND: Neuropathology of frontotemporal lobar degeneration is variable and relationship between the pathology and the clinical presentation remains uncertain. Abnormal deposits of hyperphosphorylated and ubiquitinated tau protein are present in 30% of cases, which include the classic presentation of Pick disease with argyrophilic, intraneuronal inclusions known as Pick bodies. This study aimed to improve...
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