Article
Multiple genetic loci modulate lung adenocarcinoma clinical staging.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2011
Frullanti Elisa, Galvan Antonella, Falvella Felicia S, Manenti Giacomo, Colombo Francesca, Vannelli Alberto, Incarbone Matteo, Alloisio Marco, Nosotti Mario, Santambrogio Luigi, Gonzalez-Neira Anna, Pastorino Ugo, Dragani Tommaso A
Abstract excerpt
PURPOSE: The main prognostic factor of lung cancer patient outcome is clinical stage, a parameter of tumor aggressiveness. Our study was conducted to test whether germ line variations modulate individual differences in clinical stage. EXPERIMENTAL DESIGN: We conducted a case-only genome-wide association study (GWAS) using a 620,901 single-nucleotide polymorphism (SNP) array in a first series of 600 lung...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.